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Factors Influencing Cancer Risk
Categories of data points used in the new predictive risk model
Primary Sources
Cancer | Definition, Causes, Types, & Treatment | Britannica
Top Questions What characterizes cancer as a disease? What are the two major categories of tumors? How can the global cancer burden be reduced? News • cancer, group of more than 100 distinct diseases characterized by the uncontrolled growth of abnormal cells in the body.Though cancer has been known since antiquity, some of the most significant advances in scientists’ understanding of it have been made since the middle of the 20th century. Those advances led to major improvements in cancer treatment, mainly through the development of methods for timely and accurate diagnosis, selective surgery, radiation therapy, chemotherapeutic drugs, and targeted therapies (agents designed against specific molecules involved in cancer).Advances in treatment have succeeded in bringing about a decrease in cancer deaths, though mainly in developed countries. Indeed, cancer remains a major cause of sickness and death throughout the world. By 2022 the number of new cases diagnosed annually had risen to nearly 20 million, more than half of them in less-developed countries, and the number of deaths from cancer in 2022 was 9.7 million worldwide. About 70 percent of cancer deaths were in low- and middle-income countries.The World Health Organization (WHO) has estimated that the global cancer burden could be reduced by as much as 30 to 50 percent through prevention strategies, particularly through the avoidance of known risk factors. In addition, laboratory investigations aimed at understanding the causes and mechanisms of cancer have maintained optimism that the disease can be controlled. Through breakthroughs in cell biology, genetics, and biotechnology, researchers have gained a fundamental understanding of what occurs within cells to cause them to become cancerous. Those conceptual gains are steadily being converted into actual gains in the practice of cancer diagnosis and treatment, with notable progress toward personalized medicine, in which therapy is tailored to individuals according to biological anomalies unique to their disease. Personalized medicine is considered a promising area of progress yet for modern cancer therapy. Malignant tumors and benign tumors Cancer incidence and mortality in the United StatesOverall cancer mortality in the United States has dropped consistently since the early 2000s, driven mostly by sharp declines in smoking-related cancers. However, incidence trends differ—falling in men but rising slightly in women.Tumors, or neoplasms (from Greek n...
Cancer News -- ScienceDaily
Mar. 30, 2026 A large U.S. study reveals that more than a quarter of people with hard-to-treat high blood pressure may have an overlooked hormone problem. Elevated cortisol—often linked to stress—was found in ... Mar. 30, 2026 A powerful cholesterol-lowering drug may be changing the rules of heart disease prevention. Researchers found that evolocumab, typically used for people who already have cardiovascular disease, can ... Mar. 29, 2026 A major new U.S. cholesterol guideline is shifting the focus toward earlier, more personalized prevention of heart disease. It urges people to start screening sooner—sometimes even in ... Apr. 6, 2026 Scientists have identified a potential new weapon against hepatitis E, a virus with no approved treatment and tens of thousands of deaths each year. The drug bemnifosbuvir, currently in trials for ... Mar. 27, 2026 Scientists have uncovered a hidden reason why cancer treatments don’t work equally well for everyone. Certain drugs can become trapped inside lysosomes within tumor cells, forming slow-release ... Mar. 20, 2026 A shingles vaccine might double as a powerful heart protector. In people already at high risk, it cut major cardiac events by 46% and deaths by an impressive 66% within a year. Scientists think ... Mar. 15, 2026 A major clinical trial has delivered an unexpected twist in the search for ways to fight COVID-19 and its lingering effects. Researchers at Mass General Brigham found that taking high doses of ... Mar. 17, 2026 mRNA vaccines saved millions of lives during COVID-19 but have limitations like waning immunity and complex production. Scientists are now testing a new platform called DoriVac, which uses folded DNA ... Mar. 13, 2026 A severe case of COVID-19 or influenza could increase the risk of lung cancer later on, according to new research. Scientists discovered that serious viral infections can alter immune cells in the ... Mar. 9, 2026 Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ... Mar. 6, 2026 Researchers created an AI-driven liquid biopsy that scans patterns in fragments of DNA circulating in the blood. The system detected early liver fibrosis and cirrhosis—conditions that often go ... Mar. 3, 2026 Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemother...
2026 Cancer Prevention and Early Detection Month Toolkit
This toolkit includes resources, posts to use on social media, and ideas for use throughout the month of April. View the Resource (PDF)
OnlineFirst - American Association for Cancer Research
Molecular Cancer Signal Localization in MCED Testing Minimizes Radiation and Imaging Burden Compared with Whole-body Imaging Approaches Mylynda Massart; Sana Raoof; Earl Hubbell; Eric A. Klein Cancer Prev Res (Phila) (2026) Abstract View article Supplementary data
