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Fentanyl-Related Deaths in Dallas County
Comparison of fentanyl-related deaths in 2023 and 2024 in Dallas County.
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Government partnership to tackle fentanyl use in Tucson
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Environmental enrichment found to weaken stress-triggered fentanyl relapse
Combating the opioid crisis relies on identifying new prevention strategies for problematic fentanyl use. In a collaboration between Washington State University and Washington University in St. Louis, researchers led by Jose Moron tested whether enriching a rat's environment can reduce fentanyl use and relapse. The researchers housed rats individually in either standard conditions or environments with new objects and measured fentanyl use across stages modeling human addiction: ongoing use, quitting, and relapse triggered by stress. Environmental enrichment reduced fentanyl intake over time and helped animals stop seeking the drug faster. Notably, when exposed to a stressful trigger, rats in enriched environments showed a much weaker relapse response compared to those in standard conditions. Rats in enriched environments also had lower levels of stress hormones, which were linked to relapse in those with standard conditions. According to the researchers, their work suggests that supplying rats with new objects in nonsocial environments can protect against fentanyl use and relapse. Says Jose Moron-Concepcion, "Because these strategies do not rely on social interaction, they may be easier to implement in real-world settings, including treatment programs and recovery environments. More broadly, this work highlights the powerful role of the environment and stress in addiction. Enrichment-based approaches could complement existing treatments and offer a scalable way to reduce opioid use and relapse risk." Source:Journal reference:Higginbotham, J. A., et al. (2026). Environmental Enrichment Attenuates Fentanyl-Seeking Behavior and Protects Against Stress-Induced Reinstatement in Both Male and Female Rats. eNeuro. DOI: 10.1523/ENEURO.0447-25.2026. https://www.eneuro.org/content/early/2026/03/16/ENEURO.0447-25.2026 Suggested Reading Terms While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided. Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles. Please do not ask questions that use sensitive or confidential information. Read the full Terms & Conditions.
Historic decline in U.S. overdose deaths threatened by changing street ...
A forensic chemist with the Drug Enforcement Administration holds vials of fentanyl pills at a DEA research laboratory in this file photo. Fentanyl deaths are plunging in the U.S, but the recovery is threatened by a new "synthetic soup" of toxic street drugs.
New Study Shows Limitations of Naloxone in Reversing Overdoses from ...
A new study exposes challenges in reversing opioid overdoses with naloxone when potent synthetic drugs like fentanyl and sufentanil are involved, according to a study in the May 2026 issue of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA). The findings raise important alarms for health care professionals and the public as the opioid crisis ...
